Efficacy

Testogel^® restores testosterone to within the normal range. Normal testosterone levels were achieved at day 182 in 82.2% (139/169) of hypogonadal men treated with an optimised dose, in a randomised placebo-controlled trial involving 274 patients.¹

Physical

Kaufman et al evaluated the efficacy of titrated doses of Testogel^® in 274 testosterone deficient men* who applied the gel daily for 182 days.¹

Efficacy

• Following titration, significantly more subjects receiving active treatment (range 81.6% to 82.5%) had testosterone values within the eugonadal range compared with placebo (range 28.6% to 37.0%) on all study days (p< 0.0001)

Safety

• A similar percentage of serious treatment-emergent adverse events (TEAEs) occurred in the Testogel^® (2.1%) and placebo groups (2.5%)

*Inclusion criteria: 18 to 80 years of age; Morning total testosterone < 10.4 nmol/L; Body Mass Index: 18 kg/m² to 40 kg/m²

Quality of life

The time required for testosterone therapy (TTh) to improve symptoms of testosterone deficiency (TD) varies (dependent on the organ/process that is affected) but positive effects start within just 3–4 weeks and can start to have an impact on the day-to-day lives of patients. Such effects include (vs. baseline):^2,3

For further details regarding the efficacy time frames associated with alleviation of symptoms refer to time to symptom improvement.